Fundamental replenishing anti-ageing care

    Re-substances the skin. Durably restores facial support. Skin regains extreme comfort.
    Extra-rich texture.

    40 ml tube


    Sagging of facial features. Loss of cutaneous substance. Extreme dryness.
    Mature skin innovation :
    An association of LINACTYL + PRO-XYLANE ™, an exclusive regenerating complex that targets the fundamental dermis to reactivate tissue support cells*.    
    Extra-rich, extreme comfort texture.
    *In vitro test.

    Product efficacy

    Clinical tests have demonstrated SUBSTIANE's effect on skin substance.
    At 3 months:
    Fuller (the skin is firmer) +28.9%,
    Density +17.8%,
    Wrinkles (length) -21.7%

    Texture & application

    Apply morning and/or evening to the entire face and neck. Tolerance tested under dermatological supervision.
    SUBSTIANE EXTRA-RICHE packshot from Substiane, by La Roche-Posay

    Our safety

    Safety standards beyond international cosmetics regulations.