Substiane packshot from Substiane, by La Roche-Posay


Fundamental replenishing anti-ageing care


Re-substances the skin. Durably restores facial support. Skin regains intense comfort.

40 ml tube

Substiane packshot from Substiane, by La Roche-Posay


Sagging of facial features. Loss of cutaneous substance. Dryness.
Mature skin innovation :
An association of LINACTYL + PRO-XYLANE ™, an exclusive regenerating complex that targets the fundamental dermis to reactivate tissue support cells*.              
Rich, intense comfort texture.
*In vitro test.

Product efficacy

Clinical tests have demonstrated SUBSTIANE's effect on skin substance.
At 3 months:
Fuller (the skin is firmer) +28.9%,
Density +17.8%,
Wrinkles (length) -21.7%


Skin regains comfort and radiance. Day after day, skin is re-plumped, features are visibly lifted and the facial support structure is reinforced.

Application advice

Apply morning and/or evening to the entire face and neck. Tolerance tested under dermatological supervision. Paraben-free.


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