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Retinol: The dermatologist's powerhouse molecule

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The most striking signs of skin aging are not inherent to the passage of time: they are directly triggered by external aggressors in our environment. Skin research scientists call this environmental aging. Accentuated wrinkles, complexion graying, age spots...
To counteract and reverse these signs, it would take a pluripotent genius molecule, the dermatologist's trusted ally: Retinol.

"Retinol is without a doubt the molecule best-suited to fighting the signs of photo-aging." Professor Christopher Griffiths, Manchester University*.

* Matinées scientifiques meeting, L'Oréal Cosmétique Active, Asnières, 2009

The epidermal protection vitamin

Discovered in 1913, Retinol is the naturally-occurring active form of vitamin A, which plays an essential role in maintaining skin's barrier function. In fact, patients suffering from retinol deficiency could develop hyperkeratinized, dry and rough skin - features of a prematurely aged epidermis.
Applied topically, Retinol has uniquely comprehensive effects on aged skin:

  • At the surface: Retinol smoothes and evens out the complexion, helping fight age spots and grayness.
  • In-depth: it safeguards the skin's support structures to attenuate wrinkles.

Retinol: a shining star at dermatologists'... but not without constraints

This dermatological reference molecule has also been synonymous with tolerance issues and formulation challenges. Indeed, up until recently, it simply was not a viable option for patients with sensitive skin. Women would complain of peeling, redness and discomfort. Besides, Retinol had been reserved for nocturnal application due to its fragile structure and photosensitizing effects. But not every retinol would be created equal...

2010 - La Roche-Posay creates the 1st retinol suitable for sensitive skin

A fundamental milestone in the history of Retinol was marked in 2010. La Roche-Posay dermatological laboratories launched the world's first Progressive Release Retinol for more controlled efficacy and unprecedented tolerance:
Pure Retinol is combined with progressive release retinol, forming a reservoir of the molecule within the skin for slow release and perfect tolerance, even on sensitive skin.

2016 - La Roche-Posay goes beyond, with Retinol for dayuse

Skincare engineers faced a final challenge in optimizing the use of this pluripotent molecule: formulating it for daytime use. Indeed it is during the day, when skin is over-exposed to environmental stressors, that the corrective power of Retinol is most needed.

In 2016, Retinol has finally been captured within an active environmental multi-shield:

  • Anti-long UVA and UVB SPF 30 to prevent age spots, dehydration and roughness
  • Anti-oxidant with Carnosine to combat in-depth damage leading to wrinkles and boost the energy metabolism of skin's collagen-making cells, fibroblasts
  • Anti-pollution with an anti-adhesion texture to avoid complexion graying and dullness due to pollution particles
Protected against environmental aggressors, skin is free to channel its energy into maintaining healthy, youthful tissue as well as reap the full benefits of the benchmark corrective molecule.

Recognized as one the best anti-ageing molecules, Retinol has been part of dermatologists' arsenal for decades.
Committed to supporting advancements in dermatology, La Roche-Posay has made major breakthroughs in improving and facilitating the use of this reference molecule. It is far from finished unlocking its best anti-aging secrecy!

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